US Patent Issued to Thrombolytic Science on March 31 for "Methods for safe and effective thrombolysis using sequential administration of tissue plasminogen activator and mutant pro-urokinase" (Massachusetts Inventor)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,301, issued on March 31, was assigned to Thrombolytic Science LLC (Cambridge, Mass.).

"Methods for safe and effective thrombolysis using sequential administration of tissue plasminogen activator and mutant pro-urokinase" was invented by Victor Gurewich (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods for safe and effective thrombolysis in therapy for human subjects with symptoms of a potential stroke or acute myocardial infarction ("AMI") using a sequential administration of a low dose bolus of human tissue plasminogen activator ("tPA") followed by an infusion of a mutant form of human pro-urokinase ("pro...