US Patent Issued to THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL on Sept. 22 for "RNA-targeting ligands, compositions thereof, and methods of making and using the same" (North Carolina Inventors)

ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,741,945, issued on Sept. 22, was assigned to THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, N.C.).

"RNA-targeting ligands, compositions thereof, and methods of making and using the same" was invented by Kevin Weeks (Carrboro, N.C.), Jeffrey Aube (Chapel Hill, N.C.), Kelin Li (Chapel Hill, N.C.) and Meredith Zeller (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure is directed to compounds that bind to a target RNA molecule, such as a TPP riboswitch, compositions comprising the compounds, and methods of making and using the same. The compounds contain two structurally different fragments that allow for binding wit...