US Patent Issued to The University of North Carolina at Chapel Hill on April 7 for "Potentiation of antibiotic effect" (North Carolina Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,594,289, issued on April 7, was assigned to The University of North Carolina at Chapel Hill (Chapel Hill, N.C.).

"Potentiation of antibiotic effect" was invented by Brian Conlon (Durham, N.C.), Sarah Conlon (Durham, N.C.) and Lauren Radlinski (Carrboro, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compositions, kits and methods using combinations of surfactants or cell wall-hydrolyzing enzymes with antibiotics to potentiate the antibiotic effect against bacterial infections. In some embodiments, the surfactant is a pore-forming biosurfactant such as rhamnolipids and the antibiotic is an aminoglycoside antibiotic s...