ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,706,227, issued on Aug. 11, was assigned to The University of Chicago (Chicago).

"Methods and compositions for treating cancer with von Willebrand factor peptide linked to immunotherapeutic antibodies" was invented by Jeffrey A. Hubbell (Chicago), Jun Ishihara (Chicago), Ako Ishihara (Chicago), Kazuto Fukunaga (Chicago) and Melody Swartz (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "The methods and compositions described herein address the need in the art by providing compositions and methods for a therapy with an antibody that is specifically targeted to and/or retained intra- or peri-tumorally, limiting systemic exposure and reducing side-ef...