ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,566, issued on March 17, was assigned to The University of British Columbia (Vancouver, Canada).

"Methods and compositions for modulating plasminogen" was invented by Christian J. Kastrup (Milwaukee), Amy W. Strilchuk (Vancouver, Canada), Jerry Leung (Richmond, Canada), Pieter R. Cullis (Vancouver, Canada) and Madelaine Robertson (Vancouver, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a duplex or single-stranded siRNA molecule against plasminogen, the siRNA molecule containing modified or unmodified nucleotides and wherein at least one strand of the duplex or the single-stranded siRNA has a sequence that ha...