ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,775,001, issued on Oct. 27, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Md.).

"Adaptive perfusion systems and methods for drug release testing" was invented by Xiaoming Xu (Columbia, Md.), Deval Patel (Frederick, Md.) and Ying Zhang (Centreville, Va.).

According to the abstract* released by the U.S. Patent & Trademark Office: "An in vitro release test (IVRT) method and system is provided for drug release testing. The IVRT method, referred to herein as adaptive perfusion, employ tangential-flow filtration (TFF), where released drug products that are smaller than a molecular weight cutoff (MWCO) ...