US Patent Issued to The Trustees of the University of Pennylvania on April 7 for "Compositions useful for treating GM1 gangliosidosis" (Connecticut, Pennsylvania, Louisiana Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,594,327, issued on April 7, was assigned to The Trustees of the University of Pennylvania (Philadelphia).

"Compositions useful for treating GM1 gangliosidosis" was invented by James M. Wilson (Philadelphia), Christian Hinderer (New Orleans) and Nathan Katz (Stamford, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A recombinant adeno-associated virus (rAAV) comprising an AAVhu68 capsid and a vector genome comprising a lysosomal beta-galactosidase gene (for example, galactosidase beta 1 gene, GBL1) is provided (i.e., rAAVhu68.GBL1). Also provided a composition containing an effective amount of rAAVhu68.GBL1 to ameliorate symptoms of GM1 gangliosidos...