US Patent Issued to The Trustees of the University of Pennsylvania on July 14 for "Trophin genome editing for treating Duchenne Muscular Dystrophy (DMD)" (Pennsylvania Inventor)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,680,100, issued on July 14, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Trophin genome editing for treating Duchenne Muscular Dystrophy (DMD)" was invented by Tejvir S. Khurana (Narberth, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to compositions and methods for improving a dystrophic phenotype in a human subject having myopathies, such as Duchenne Muscular Dystrophy (DMD). In one embodiment, the invention relates to compositions comprising an adenoviral vector targeting the let-7c miRNA binding sequence in 3'-UTR genome editing of the utrophin gene and methods of treatment comprising adm...