US Patent Issued to The Trustees of the University of Pennsylvania on Aug. 4 for "Small molecules for dual function positron emission tomography (PET) and cell suicide switches" (Pennsylvania Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,697,403, issued on Aug. 4, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Small molecules for dual function positron emission tomography (PET) and cell suicide switches" was invented by Michael Farwell (Wynnewood, Pa.), Mark Sellmyer (Philadelphia) and Katheryn M. Lohith (Lansdale, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes an engineered cell comprising a chimeric antigen receptor (CAR) further comprising a nucleic acid molecule comprising a suicide gene comprising a ligand binding domain and a suicide domain wherein the ligand binding domain is capable of binding to radiolabeled tra...