US Patent Issued to The Trustees of the University of Pennsylvania on April 14 for "Adeno-associated virus (AAV) vector and uses therefor" (Pennsylvania Inventor)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,989, issued on April 14, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Adeno-associated virus (AAV) vector and uses therefor" was invented by Qiang Wang (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are engineered nucleic acid sequences encoding AAVhu68 which provide improved yields of packaged AAVhu68 viral particles. Also provided is a packaging host cell comprising the engineered nucleotide sequence and methods of using same to product recombinant AAVhu68 vectors useful for gene delivery. Further provided are production cell supernatants comprising improved yields of recombinant AA...