ALEXANDRIA, Va., July 16 -- United States Patent no. 12,668,616, issued on June 30, was assigned to The Trustees of the University of Pennsylvania (Philadelphia) and Inovio Pharmaceuticals Inc. (Plymouth Meeting, Pa.).
"WT1 vaccine" was invented by David B. Weiner (Merion, Pa.), Jian Yan (Wallingford, Pa.) and Jewell Walters (Ramona, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated WT1 antigen. Vectors, compositions and vaccines comprising one or more nucleic acid sequences that encode a mutated WT1 antigen are disclosed. Methods of treating an individual who has a WT1-expressing tumor and met...