US Patent Issued to THE TRUSTEES OF INDIANA UNIVERSITY on July 28 for "Methods to sensitize cancer cells to immune attack using atractylenolide I" (Indiana Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,691,093, issued on July 28, was assigned to THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Ind.).

"Methods to sensitize cancer cells to immune attack using atractylenolide I" was invented by Xiongbin Lu (Carmel, Ind.), Xinna Zhang (Carmel, Ind.) and Kevin Van Der Jeught (Indianapolis).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compositions and methods to induce or increase immunogenicity in cancerous cells comprising contacting the cancerous cells with atractylenolide I (ATT-I). In some embodiments, the methods include contacting the cancerous cells with ATT-I in combination with a cancer therapeutic agent."

The p...