US Patent Issued to The Trustees of Columbia University in the City of New York on April 21 for "Methods to induce terminal differentiation in stem cells by interfering with DNA replication, methods of inducing pancreatic differentiation, and differentiated cells obtained thereof" (New York, New Jersey Inventors)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,605,407, issued on April 21, was assigned to The Trustees of Columbia University in the City of New York (New York).

"Methods to induce terminal differentiation in stem cells by interfering with DNA replication, methods of inducing pancreatic differentiation, and differentiated cells obtained thereof" was invented by Dietrich Egli (New York) and Lina Sui (Fort Lee, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The current invention provides for methods and systems of inducing cell cycle exit and terminal differentiation in stem cells undergoing differentiation into various mature cell types in particular pancreatic endocrine cells. The current in...