ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,173, issued on March 24, was assigned to THE SCRIPPS RESEARCH INSTITUTE (La Jolla, Calif.).

"Methods for disease treatment and drug discovery" was invented by Chao Wang (San Diego) and William E. Balch (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Drug administration is performed in view of variation spatial profiling (VSP) of patients or potential patients. Spatial-covariance (SCV) relationships relate the position of the disease-associated variant in the polypeptide chain with cell-based models and clinical features of disease. An understanding of SCV relationships for a sparse collection of known fiduciary variants can be used to gen...