US Patent Issued to The Rockefeller University on March 17 for "Antibodies to CD40 with enhanced agonist activity" (New York Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,315, issued on March 17, was assigned to The Rockefeller University (New York).

"Antibodies to CD40 with enhanced agonist activity" was invented by Jeffrey V. Ravetch (New York) and Rony Dahan (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are agonistic antibodies, or antigen binding portions thereof, that bind to human CD40. Such antibodies optionally comprise Fc regions with enhanced specificity for FcGammaRIIb. The invention also provides methods of treatment of cancer or chronic infection by administering the antibodies of the invention to a subject in need thereof."

The patent was filed on July 31, 2023, under Applic...