US Patent Issued to The Research Foundation for The State University of New York on May 12 for "Compositions and methods for reducing off-target toxicity of antibody drug conjugates" (New York Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,123, issued on May 12, was assigned to The Research Foundation for The State University of New York (Amherst, N.Y.).

"Compositions and methods for reducing off-target toxicity of antibody drug conjugates" was invented by Joseph P. Balthasar (Lancaster, N.Y.), Brandon M. Bordeau (Amherst, N.Y.), Toan Duc Nguyen (Amherst, N.Y.) and Joseph Ryan Polli (Amherst, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compositions and methods for reducing off-target toxicity of antibody-drug conjugates (ADCs). The compositions comprise an ADC, and an agent targeted to the drug (payload) that is delivered by or derived from the ADC. The ADC and the...