ALEXANDRIA, Va., March 24 -- United States Patent no. 12,583,845, issued on March 24, was assigned to The Research Foundation for The State University of New York (Albany, N.Y.).
"Compositions and methods for treating diseases, disorders and conditions involving trinucleotide repeats" was invented by Hormoz Mazdiyasni (Menands, N.Y.) and John Andrew Berglund (Menands, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides compositions that inhibit microsatellite promoted expression of deleterious expansions by targeting expanded CTG DNA as well as methods using such compositions for use in treating or ameliorating the effects of a medical condition involving trinucleotide repeats...