ALEXANDRIA, Va., May 12 -- United States Patent no. 12,623,003, issued on May 12, was assigned to THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Mich.).

"Three-dimensional microporous scaffold device for cell culture" was invented by Lonnie D. Shea (Ann Arbor, Mich.), Richard Youngblood (Ann Arbor, Mich.) and Tadas Kasputis (Ann Arbor, Mich.).

According to the abstract* released by the U.S. Patent & Trademark Office: "An in vitro method of preparing insulin-producing cell clusters for transplantation into a subject, comprising (a) seeding pancreatic progenitor cells onto a three-dimensional, porous scaffold at a seeding density greater than about 12.5 million cells per cm3 of scaffold and less than about 150 million cells per cm3 o...