US Patent Issued to The Regents of the University of California on Sept. 29 for "Methods for X chromosome reactivation" (California Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,746,254, issued on Sept. 29, was assigned to The Regents of the University of California (Oakland, Calif.).

"Methods for X chromosome reactivation" was invented by Kathrin Plath (Los Angeles), Amy Pandya-Jones (Los Angeles), Shawn Tan (Los Angeles), Douglas Black (Los Angeles) and Giolanta Markaki (Los Angeles).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to a method for re-activating the X-chromosome in cells comprising administering a SPEN inhibitor to the cell. Further aspects relate to a method for re-activating the X-chromosome in a subject in need thereof, the method comprising administering a SPEN inhibitor to t...