US Patent Issued to The Regents of the University of California on Sept. 15 for "Gene editing of monogenic disorders in human hematopoietic stem cells-correction of x-linked hyper-IGM syndrome (XHIM)" (California Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,720, issued on Sept. 15, was assigned to The Regents of the University of California (Oakland, Calif.).

"Gene editing of monogenic disorders in human hematopoietic stem cells-correction of x-linked hyper-IGM syndrome (XHIM)" was invented by Joseph Long (Studio City, Calif.), Donald B. Kohn (Tarzana, Calif.) and Caroline Y. Kuo (Beverly Hills, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are methods of treating X-Linked Hyper-IgM Syndrome (XHIM) in a mammal. Methods include: (i) providing differentiated T cells and/or stem/progenitor cells obtained from the mammal; and (ii) performing a targeted insertion of a corrective CD...