US Patent Issued to The Regents of the University of California on Oct. 6 for "Methods and materials for ameliorating creatine deficiency disorders" (California Inventor)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,751,995, issued on Oct. 6, was assigned to The Regents of the University of California (Oakland, Calif.).

"Methods and materials for ameliorating creatine deficiency disorders" was invented by Gerald Lipshutz (Los Angeles).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention disclosed herein provides methods and materials useful in gene therapy regimens designed to treat creatine deficiency disorders. Creatine deficiency disorders are inborn errors of creatine metabolism, an energy homeostasis molecule. One of these, guanidinoacetate N-methyltransferase (GAMT) deficiency, has clinical characteristics that include features of autism, self-mutilatio...