ALEXANDRIA, Va., May 26 -- United States Patent no. 12,636,345, issued on May 26, was assigned to The Regents of the University of California (Oakland, Calif.).
"Methods of treating glioblastomas" was invented by Wendell A. Lim (San Francisco), Hideho Okada (San Francisco), Kole T. Roybal (San Francisco), Joseph H. Choe (San Francisco) and Payal B. Watchmaker (San Francisco).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is a method of treating a subject for a glioblastoma, the method comprising: administering to the subject an immune cell genetically modified with: (a) a nucleic acid sequence encoding a binding triggered transcriptional switch (BTTS) that binds to a priming antigen that is ti...