US Patent Issued to The Regents of the University of California on May 19 for "Peptide deficient-MHC class I/chaperone compositions and methods" (Pennsylvania Inventor)

ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,606, issued on May 19, was assigned to The Regents of the University of California (Oakland, Calif.).

"Peptide deficient-MHC class I/chaperone compositions and methods" was invented by Nikolaos Sgourakis (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions that include stable peptide deficient MHC class I/chaperone complexes and methods of making and using such complexes are provided. In particular embodiments, such peptide deficient MHC class I/chaperone complexes are used to form peptide MHC class I (pMHC-I) multimers useful for high throughput applications, such as, for the detection of antigen specific T cells and characteriz...