US Patent Issued to The Regents of the University of California on March 3 for "Compositions and methods for targeted delivery of CRISPR-Cas effector polypeptides and transgenes" (California Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,647, issued on March 3, was assigned to The Regents of the University of California (Oakland, Calif.).

"Compositions and methods for targeted delivery of CRISPR-Cas effector polypeptides and transgenes" was invented by Jennifer A. Doudna (Berkeley, Calif.), Jennifer Hamilton (Berkeley, Calif.) and Connor Tsuchida (Berkeley, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides virus-like particles (VLPs) comprising: i) a CRISPR-Cas effector polypeptide; ii) a recombinant lentivirus comprising a nucleotide sequence encoding a therapeutic polypeptide having a length of from about 250 amino acids to about 3,000 amino aci...