US Patent Issued to The Regents of the University of California on March 24 for "Persistent memory T-cell responses to cancer and infectious-disease antigens by manipulation of amino acid-catabolism pathways" (California Inventor)

ALEXANDRIA, Va., March 24 -- United States Patent no. 12,582,709, issued on March 24, was assigned to The Regents of the University of California (Oakland, Calif.).

"Persistent memory T-cell responses to cancer and infectious-disease antigens by manipulation of amino acid-catabolism pathways" was invented by Dennis Hartigan-O'Connor (Oakland, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are recombinant polynucleotides including a first nucleic acid sequence encoding an antigen, and a second nucleic acid sequence encoding an enzyme of an amino acid catabolic pathway. The provided recombinant polynucleotides are particularly useful for inducing long-lived immune responses having improv...