ALEXANDRIA, Va., April 21 -- United States Patent no. 12,605,336, issued on April 21, was assigned to The Regents of the University of California (Oakland, Calif.).
"Fusogenic liposome-coated porous silicon nanoparticles" was invented by Michael J. Sailor (La Jolla, Calif.), Byungji Kim (Cambridge, Mass.) and Jinyoung Kang (La Jolla, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure describes a fusogenic liposome-coated porous silicon nanoparticles for high loading efficiency of anionic payloads (small molecules, dyes, nucleic acids), and for non-endocytic delivery of hydrophilic and lipophilic payloads by membrane fusion. The liposome coating can be further modified with targeting peptide...