ALEXANDRIA, Va., April 15 -- United States Patent no. 12,599,608, issued on April 14, was assigned to The Regents of the University of California (Oakland, Calif.) and The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone (San Francisco).

"Methods for treating cardiac valve disease" was invented by Christina Theodoris (San Francisco) and Deepak Srivastava (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods of treating cardiac valve disease, e.g., calcific aortic valve disease (CAVD), by administering to a subject in need thereof a therapeutically effective amount of a compound of any one of Formulae I-X or a ...