ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,747,454, issued on Sept. 29, was assigned to The Regents of the University of California (Oakland, Calif.) and THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, Calif.).
"Self-inactivating lentiviral vector comprising a FoxP3 expression cassette" was invented by Donald B. Kohn (Tarzana, Calif.), Maria Grazia Roncarolo (Menlo Park, Calif.), Roger Paul Hollis (Los Angeles), Katelyn E. Masiuk (Santa Monica, Calif.) and Rosa Bacchetta (Menlo Park, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "In various embodiments, lentiviral vectors expressing FoxP3 using the endogenous gene elements to regulate physiologic gene expression...