ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,741,949, issued on Sept. 22, was assigned to The Regents of the University of California (Oakland, Calif.) and Amydis Inc. (San Diego).
"Amyloid targeting agents and methods of using the same" was invented by Jerry Yang (La Jolla, Calif.), Emmanuel A. Theodorakis (San Diego) and Stella Sarraf (Beverly Hills, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compou...