ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,643, issued on March 3, was assigned to The Medical College of Wisconsin Inc. (Milwaukee).

"Alpha-galactosidase protein for enzyme replacement therapy (ERT) and methods of use" was invented by Jeffrey A. Medin (Shorewood, Wis.) and Simone Scalia (Milwaukee).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides less immunogenic mutant Alpha-galactosidase A protein (Alpha-gal), methods of making and methods of use. The less immunogenic mutant Alpha-gal of the present invention provides a reduced immune response when administered to a subject."

The patent was filed on Sept. 18, 2020, under Application No. 17/640,246.

*For furt...