US Patent Issued to The Johns Hopkins University on June 23 for "Non-immunosuppressive FK506 analogs and use thereof" (Maryland Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,493, issued on June 23, was assigned to The Johns Hopkins University (Baltimore).

"Non-immunosuppressive FK506 analogs and use thereof" was invented by Jun O. Liu (Clarksville, Md.), Zhaoli Sun (Perry Hall, Md.), Brandon J. Peiffer (Rosedale, Md.), Yuefan Wang (Nottingham, Md.), Le Qi (Baltimore), Zufeng Guo (Baltimore), Hanjing Peng (Columbia, Md.) and Ali Ahmadi (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a new class of non-immunosupressive FK506 analogs which are FRBP-selective, small-molecule BMP agonists with modest potency therepeutics for tissue repair and regeneration. Also disclosed herein are me...