ALEXANDRIA, Va., June 2 -- United States Patent no. 12,642,817, issued on June 2, was assigned to The Johns Hopkins University (Baltimore).

"Nanoparticle modification of human adipose-derived mesenchymal stem cells for treating brain cancer and other neurological diseases" was invented by Alfredo Quinones-Hinojosa (Bel Air, Md.) and Jordan Green (Nottingham, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The presently disclosed subject matter provides compositions, methods, and kits for transfecting adipose-derived mesenchymal stem cells (AMSCs) in freshly extracted adipose tissue using nanoparticles comprising biodegradable polymers self-assembled with nucleic acid molecules. The presently disclosed sub...