US Patent Issued to THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH on April 7 for "Thiosemicarbazates and uses thereof" (New York Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,233, issued on April 7, was assigned to THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, N.Y.).

"Thiosemicarbazates and uses thereof" was invented by Yousef Al-Abed (Manhasset, N.Y.) and Ahmad Altiti (Manhasset, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Thioesters, thiocarbamates, thiocarbazates, semithiocarbazates, peptides, aza-amino acid conjugates, and azapeptides; and a chemoselective and site-specific functionalization protocol of protected thiocarbazates and semithiocarbazates are described. The protocol features the use of Mitsunobu reaction to alkylate specifically the nitrogen atom close to the acylthiol moiety with alco...