US Patent Issued to The Curators of the University of Missouri on June 9 for "Compositions and methods of treatment comprising tumor-targeting bacteria and chemotherapy or immunotherapy agent" (Missouri Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,648,970, issued on June 9, was assigned to The Curators of the University of Missouri (Columbia, Mo.).

"Compositions and methods of treatment comprising tumor-targeting bacteria and chemotherapy or immunotherapy agent" was invented by Chiswili Yves Chabu (Columbia, Mo.), Bakul Dhagat (Columbia, Mo.) and Robert Kazmierczak (Columbia, Mo.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to a composition of a biologically pure isolate of the genus Salmonella comprising archival strain CRC1674, wherein the isolate further comprises a disruption of at least one gene selected from the group consisting of aroA, rfaH, and thyA and a ...