US Patent Issued to THE CHILDREN'S MEDICAL CENTER on June 23 for "ADAMTS13 treatment to enhance graft survival" (Singaporean, American Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,661,390, issued on June 23, was assigned to THE CHILDREN'S MEDICAL CENTER Corp. (Boston).

"ADAMTS13 treatment to enhance graft survival" was invented by Denisa D. Wagner (Dover, Mass.) and Siu Ling Wong (Singapore).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides a method for treating and/or preventing graft rejection with A Disintegrin And Metalloproteinase with Thrombospondin type 1 motif, member-13 (ADAMT S13). The disclosure provides a method for increasing ADAMTS13-mediated von Willebrand factor (VWF) cleavage in a subject that received a graft by administering ADAMTS13. The disclosure also provides a method of determining the ...