US Patent Issued to The Children's Hospital of Philadelphia on June 16 for "Adeno-associated viral vector variants" (Pennsylvania Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,653,910, issued on June 16, was assigned to The Children's Hospital of Philadelphia (Philadelphia).

"Adeno-associated viral vector variants" was invented by Beverly Davidson (Philadelphia), Yonghong Chen (Philadelphia), Paul T. Ranum (Philadelphia) and Xueyuan Liu (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are targeting peptides and vectors containing a sequence that encodes the targeting peptides that deliver agents to specific substructures in the brain. Provided herein are viral vectors each comprising a modified capsid, wherein the modified capsid comprises at least one amino acid sequence that targets the viral vec...