US Patent Issued to The Broad Institute, Massachusetts Institute of Technology, The Brigham and Women's Hospital on April 7 for "Crispr-Cas systems having destabilization domain" (Massachusetts Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,478, issued on April 7, was assigned to The Broad Institute Inc. (Cambridge, Mass.), Massachusetts Institute of Technology (Cambridge, Mass.) and The Brigham and Women's Hospital Inc. (Boston).

"Crispr-Cas systems having destabilization domain" was invented by Amit Choudhary (Boston), Basudeb Maji (Cambridge, Mass.), Bernd Zetsche (Cambridge, Mass.) and Feng Zhang (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure includes non-naturally occurring or engineered DNA- or RNA-guided nuclease systems, comprising guide-binding adaptors each associated with at least one destabilization domain (DD), along with compositions, syst...