US Patent Issued to The Brigham and Women's Hospital on March 31 for "Antigen-presenting neutrophil-derived dendritic cells and methods of use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,589,140, issued on March 31, was assigned to The Brigham and Women's Hospital Inc. (Boston).

"Antigen-presenting neutrophil-derived dendritic cells and methods of use thereof" was invented by Tanya Mayadas (Jamaica Plain, Mass.), Vijaya Mysore (West Roxbury, Mass.), Xavier Cullere (Newton, Mass.) and Jon C. Aster (Lexington, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and compositions for use in generating or promoting an immune response to cancer or an infection, comprising promoting differentiation of neutrophils into dendritic cells using a combination of GMCSF and (i) an immune complex comprising an antigen and an antibody comprisi...