ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,699,100, issued on Aug. 4, was assigned to THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas).
"Deep learning system for predicting the T cell receptor binding specificity of neoantigens" was invented by Tianshi Lu (Dallas) and Tao Wang (Coppel, Texas).
According to the abstract* released by the U.S. Patent & Trademark Office: "Neoantigens play a key role in the recognition of tumor cells by T cells. However, only a small proportion of neoantigens truly elicit T cell responses, and fewer clues exist as to which neoantigens are recognized by which T cell receptors (TCRs). To help determine the TCRs that interact with particular neoantigens, prediction models that pr...