US Patent Issued to Tenaya Therapeutics on Feb. 17 for "Adeno-associated virus with engineered capsid" (California Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,552,838, issued on Feb. 17, was assigned to Tenaya Therapeutics Inc. (South San Francisco, Calif.).

"Adeno-associated virus with engineered capsid" was invented by Ze Cheng (South San Francisco, Calif.) and Christopher A. Reid (Walnut Creek, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides recombinant adeno-associated virus (rAAV) virions with an engineered capsid protein. In particular, the disclosure provides AAV9 virions with engineered AAV9 capsid, AAV5/9 chimeric capsid or combinatory capsid that achieves increased transduction efficiency in cardiac cells, increased cell-type selectivity, and/or other desirable ...