ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,494, issued on Feb. 24, was assigned to Temple University-Of The Commonwealth System of Higher Education (Philadelphia) and Praeventix LLC (Exton, Pa.).

"Functionalized lactams as modulators of the 5-hydroxytryptamine receptor 7 and their method of use" was invented by Daniel J. Canney (Philadelphia), Benjamin E. Blass (Philadelphia), Kevin M. Blattner (Exton, Pa.) and Douglas A. Pippin (Exton, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Pharmaceutical compositions of the invention comprise functionalized lactam derivatives of formula (I) having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxy...