US Patent Issued to Technische Universitat Munchen on March 17 for "Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof" (German Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,169, issued on March 17, was assigned to Technische Universitat Munchen (Munich).

"Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof" was invented by Daniel Di Carlo (Haimhausen, Germany) and Hans-Jurgen Wester (Schweitenkirchen/Sunzhausen, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "A ligand-SiFA conjugate compound represented by formula (1) wherein: RL is a ligand moiety which is capable of binding to prostate-specific membrane antigen (PSMA); RSiFA is a silicon-fluoride acceptor (SiFA) moiety which can be labeled with 18F or which is labeled with 18F; L is a linking moiety; RH is a hydrophilic moiety wh...