US Patent Issued to TECHNION RESEARCH & DEVELOPMENT FOUNDATION, HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT on April 21 for "Heparanase-neutralizing A54 monoclonal antibody" (Israeli Inventors)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,637, issued on April 21, was assigned to TECHNION RESEARCH & DEVELOPMENT FOUNDATION Ltd. (Haifa, Israel) and HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (Jerusalem).

"Heparanase-neutralizing A54 monoclonal antibody" was invented by Israel Vlodavsky (Mevasseret Zion, Israel) and Uri Barash (Haifa, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an heparanase-binding and heparanase-neutralizing monoclonal antibody (IgG-1 mAb A54), including its epitope (HBD-II) and mode of interaction with heparanase, pharmaceutical composition comprising same, and uses thereof e.g. for inhibiting or treating a diseas...