ALEXANDRIA, Va., July 21 -- United States Patent no. 12,685,730, issued on July 21, was assigned to TANABE PHARMA Corp. (Osaka, Japan).

"Pharmaceutical composition for keratosis and use thereof" was invented by Ryuta Saito (Osaka, Japan) and Yasuaki Matsushita (Osaka, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A pharmaceutical composition for keratosis contains 5-methyl-2-(1-piperazinyl)benzenesulfonic acid. The compound may be in a form of an anhydrate thereof, a salt thereof, a hydrate or solvate thereof, or a hydrate or solvate of a salt thereof, and the hydrate is, for example, 5-methyl-2-(1-piperazinyl)benzenesulfonic acid monohydrate. The keratosis is, for example, Darier's disease or psorias...