US Patent Issued to Takeda Pharmaceutical on June 16 for "Method for producing pyrrolidine compound" (Japanese Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,655,100, issued on June 16, was assigned to Takeda Pharmaceutical Ltd. Co. (Osaka, Japan).

"Method for producing pyrrolidine compound" was invented by Masatoshi Yamada (Osaka, Japan), Sayuri Hirano (Osaka, Japan), Osamu Yabe (Osaka, Japan), Yuichi Kajita (Osaka, Japan), Tsuneo Oda (Kanagawa, Japan), Takashi Abe (Kanagawa, Japan) and Hironori Yamashita (Kanagawa, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a method suitable for industrial production of a compound of formula (V): (V) comprising a step of subjecting a compound (IV) to an asymmetric reductive amination reaction in the presence of a metal complex compr...