ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,539, issued on April 21, was assigned to Synthon B.V. (Nijmegen, Netherlands).
"Process for preparation of apalutamide" was invented by Ondrej Hylse (Blansko, Czech Republic), David Chalupa (Blansko, Czech Republic), Bohumil Dymacek (Blansko, Czech Republic) and Marian Buchlovic (Blansko, Czech Republic).
According to the abstract* released by the U.S. Patent & Trademark Office: "The presented invention relates to a process for preparation of Apalutamide, compound (1) or a salt or a solvate thereof:The presented invention further relates to solid forms of Apalutamide, solvates of Apalutamide and to processes for preparation thereof. The presented invention also relates to solid ...