ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,177, issued on Oct. 6, was assigned to SYDDANSK UNIVERSITTET (Denmark).
"Substituted 1,2,3-triazoles as antibacterial and antifungal pleuromutilin conjugates" was invented by Poul Nielsen (Odense SV, Denmark) and Christoffer Vogsen Heidtmann (Odense M, Denmark).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds of formula (1) comprising a pleuromutilin backbone with a triazole based side-group at C22 are provided. The compounds can be used for treatment of bacterial infections and fungal infections. Importantly, infections caused by multidrug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) may be treated effectivel...