ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,487, issued on Feb. 24, was assigned to Sumitomo Pharma Co. Ltd. (Osaka, Japan).
"Crosslinked optically active secondary amine derivative" was invented by Seiji Kamioka (Toyonaka, Japan), Naoaki Shimada (Takatsuki, Japan), Wataru Hirose (Setagaya, Japan) and Hitoshi Ban (Nishinomiya, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the compound of formula (1a) wherein p is 1 or 2, R1-R4 are hydrogen atom or the like, Ring A is cycloalkylene or the like, L is single bond or the like, and R is methyl or the like, or a pharmaceutically acceptable salt thereof, which has an anticancer effect by inhibiting the binding...