US Patent Issued to STOKE THERAPEUTICS on March 17 for "Antisense oligomers for treatment of conditions and diseases" (Massachusetts Inventor)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,561, issued on March 17, was assigned to STOKE THERAPEUTICS INC. (Bedford, Mass.).

"Antisense oligomers for treatment of conditions and diseases" was invented by Isabel Aznarez (Jamaica Plain, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Alternative splicing events in SCN1A gene can lead to non-productive mRNA transcripts which in turn can lead to aberrant protein expression, and therapeutic agents which can target the alternative splicing events in SCN1A gene can modulate the expression level of functional proteins in Dravet Syndrome patients and/or inhibit aberrant protein expression. Such therapeutic agents can be used to treat a conditi...