US Patent Issued to STEMIRNA THERAPEUTICS on April 7 for "Modified nucleoside and synthetic methods thereof" (Chinese Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,279, issued on April 7, was assigned to STEMIRNA THERAPEUTICS Co. LTD. (Shanghai).

"Modified nucleoside and synthetic methods thereof" was invented by Yunsong Cai (Shanghai), Hangwen Li (Shanghai), Lianxiao Liu (Shanghai) and Ning Li (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a modified cytidine compound, i.e. a new derivative cytidine generated by adding a guanidyl at position 4 of a cytidine, and a nucleic acid containing the modified compound, for example, RNA. The nucleic acid containing the modified cytidine, especially mRNA, can significantly increase the expression quantity of the mRNA in vivo."

The patent was fil...